MicroMeasure is a scientific image analysis application for cytogeneticists and cytologists. MM is designed for the measurement of chromosomes and related structures from any suitable digitized images, such as scanned or electronically captured light- or electron micrographs. MM works with Microsoft Windows 95, 98, 2000, Millenium Edition, or NT 4.0.

This screen shot from MicroMeasure version 3.2 shows part of a set of synaptonemal complexes (SCs) from tomato ( Lycopersicon esculentum Mill.).

Two individual SCs were marked in preparation for generating measurement data (shown in blue). Kinetochores are marked in red.

(TEM micrograph courtesy of Dr. Daniel Peterson)

Screen shot from MM 3.2
Screen shot from MM 3.2 Screen shot from MM 3.2 Screen shot from MM 3.2
Screen shot from MM 3.2

Since MM is intended specifically for linear chromosome measurement (unlike other image analysis programs), characteristics commonly used by chromosome cytologists (such as centromeres, bands, fluorescent foci, etc.) may be easily marked, and standard data types (e.g. relative lengths of chromosomes or chromosome arm ratios) are computed automatically in an Excel spreadsheet.

Users may also customize the traits to be marked with MM, and using the flexible data spreadsheet, conduct more specialized analyses.

This software package is made available to researchers without cost by the Biology Department at Colorado State University. Please see the copyright notice and terms of use for more information.